SCHEMBL17835939

SCHEMBL17835939

Br[Ni]Br.CC(C)c1cccc(C(C)C)c1N=C1C(=Nc2c(C(C)C)cccc2C(C)C)c2cccc3cccc1c23

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
TSHR P16473 3/20 0.35
HSD17B10 Q99714 3/20 0.35
MAPK1 P28482 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KCNN2 Q9H2S1 5/20 0.33
KCNN3 Q9UGI6 5/20 0.33
HPGD P15428 3/20 0.33
CYP3A4 P08684 2/20 0.33
CASP1 P29466 2/20 0.33
CASP7 P55210 2/20 0.33
HIF1A Q16665 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
PABPC1 P11940 1/20 0.33
DNMT1 P26358 1/20 0.33
FAAH O00519 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12923294 0.93 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10MAPK1ATM
SCHEMBL987736 0.93 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10MAPK1ATM
SCHEMBL5138932 0.93 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10MAPK1ATM
SCHEMBL987735 0.93 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10MAPK1ATM
SCHEMBL5587463 0.92 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10MAPK1ATM
Bromide SCHEMBL8670022 0.90 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10MAPK1ATM
Hydrochloric Acid SCHEMBL8670038 0.90 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10MAPK1ATM
SCHEMBL15624658 0.88 ALDH1A1 (0.33) ALDH1A1TSHRHSD17B10MAPK1ATM
SCHEMBL19625542 0.86 POLB (0.37) ALDH1A1TSHRHSD17B10MAPK1ATM
SCHEMBL5589772 0.86 POLB (0.40) ALDH1A1TSHRHSD17B10MAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3237461-B1 PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES SABIC GLOBAL TECHNOLOGIES BV (NL) 2026-03-18 EP disclosed
CN-116874679-A Vinyl elastomer, preparation method and application thereof 海南贝欧亿科技有限公司 2023-10-13 CN disclosed
CN-116874673-A Vinyl copolymer, preparation method and application thereof 海南贝欧亿科技有限公司 2023-10-13 CN disclosed
CN-116874674-A Vinyl copolymer elastomer, preparation method and application thereof 海南贝欧亿科技有限公司 2023-10-13 CN disclosed
EP-3034545-B1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-11-04 EP disclosed
US-10787545-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first functionalized short chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-09-29 US disclosed
US-20200262983-A1 PROCESS FOR THE PREPARATION OF POLYOLEFIN-BASED GRAFT COPOLYMERS COMPRISING A FIRST FUNCTIONALIZED SHORT CHAIN BRANCHED POLYOLEFIN BLOCK AND ONE OR MULTIPLE POLYMER SIDE CHAINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-20 US disclosed
US-10717826-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first long chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-07-21 US disclosed
EP-3233974-B1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-02-19 EP disclosed
US-10472447-B2 Process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-12 US disclosed
EP-3037438-A1 Process for the preparation of a branched polyolefin SABIC Global Technologies B.V. (NL) 2016-06-29 EP disclosed
EP-3037437-A1 Process for the preparation of a polyolefin having one or multiple end-functionalized branches. SABIC Global Technologies B.V. (NL) 2016-06-29 EP disclosed
WO-2016097204-A1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
WO-2016097203-A1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AS WELL AS THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
WO-2016097207-A1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
WO-2016097208-A1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
EP-3034547-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034546-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block as well as the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034544-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034545-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed