Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415420 | 1.00 | MAPT (0.42) | MAPTHTTKMT2AMEN1NPC1 | |
| SCHEMBL418805 | 1.00 | MAPT (0.42) | MAPTHTTKMT2AMEN1NPC1 | |
| SCHEMBL10241400 | 0.90 | EGFR (0.40) | MAPTKMT2AMEN1NPC1MITF | |
| SCHEMBL415597 | 0.90 | EGFR (0.40) | MAPTKMT2AMEN1NPC1MITF | |
| SCHEMBL415596 | 0.90 | EGFR (0.40) | MAPTKMT2AMEN1NPC1MITF | |
| SCHEMBL459932 | 0.90 | MAPT (0.43) | MAPTHTTKMT2AMEN1NPC1 | |
| SCHEMBL17836754 | 0.90 | MAPT (0.43) | MAPTHTTKMT2AMEN1NPC1 | |
| SCHEMBL412716 | 0.88 | CHRNA7 (0.48) | MAPTKMT2AMEN1NPC1MITF | |
| SCHEMBL416309 | 0.88 | MEN1 (0.40) | MAPTHTTKMT2AMEN1NPC1 | |
| SCHEMBL10240649 | 0.88 | MEN1 (0.40) | MAPTHTTKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |