Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | GPR39 | O43194 | 4/20 | 0.42 |
| ▸ | VCP | P55072 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17836754 | 1.00 | MAPT (0.43) | MAPTHTTGPR39VCPLMNA | |
| SCHEMBL415420 | 0.90 | MAPT (0.42) | MAPTHTTLMNAKMT2AMEN1 | |
| SCHEMBL418805 | 0.90 | MAPT (0.42) | MAPTHTTLMNAKMT2AMEN1 | |
| SCHEMBL17836747 | 0.90 | MAPT (0.42) | MAPTHTTLMNAKMT2AMEN1 | |
| SCHEMBL416423 | 0.89 | MAPT (0.51) | MAPTHTTGPR39VCPLMNA | |
| SCHEMBL17836751 | 0.89 | MAPT (0.51) | MAPTHTTGPR39VCPLMNA | |
| SCHEMBL415522 | 0.89 | MAPT (0.51) | MAPTHTTGPR39VCPLMNA | |
| SCHEMBL415597 | 0.81 | EGFR (0.40) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10241400 | 0.81 | EGFR (0.40) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL415596 | 0.81 | EGFR (0.40) | MAPTLMNAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |