Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931040 | 0.87 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL108641 | 0.86 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL109251 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL108537 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL109074 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL109182 | 0.84 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL107522 | 0.83 | P2RX7 (0.81) | P2RX7 | |
| SCHEMBL9931044 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL109008 | 0.82 | P2RX7 (0.77) | P2RX7 | |
| SCHEMBL111226 | 0.82 | P2RX7 (0.75) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424869-B1 | 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZINE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LTD (GB) | 2016-06-22 | — | — | EP | claimed |