Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155776 | 0.88 | P2RX7 (0.79) | P2RX7TACR3 | |
| SCHEMBL159048 | 0.87 | P2RX7 (0.79) | P2RX7TACR3 | |
| SCHEMBL107142 | 0.81 | P2RX7 (0.85) | P2RX7 | |
| SCHEMBL108158 | 0.80 | P2RX7 (0.85) | P2RX7TACR3 | |
| SCHEMBL105425 | 0.80 | P2RX7 (0.86) | P2RX7 | |
| SCHEMBL107638 | 0.79 | TACR3 (0.63) | P2RX7TACR3 | |
| SCHEMBL109168 | 0.78 | P2RX7 (0.86) | P2RX7 | |
| SCHEMBL110594 | 0.76 | P2RX7 (1.00) | P2RX7TACR3 | |
| SCHEMBL109670 | 0.75 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL106936 | 0.73 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424869-B1 | 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZINE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LTD (GB) | 2016-06-22 | — | — | EP | claimed |