Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 15/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466657 | 0.85 | PTGS1 (0.64) | PTGS1P2RX1GAAAHRHSD17B10 | |
| SCHEMBL27609471 | 0.81 | PTGS1 (0.60) | PTGS1P2RX1GAAAHRHSD17B10 | |
| SCHEMBL27483851 | 0.81 | PTGS1 (0.60) | PTGS1P2RX1GAAAHRHSD17B10 | |
| SCHEMBL1863665 | 0.78 | RXFP1 (0.80) | RXFP1 | |
| SCHEMBL31424184 | 0.77 | PTGS1 (1.00) | PTGS1P2RX1GAAAHRHSD17B10 | |
| SCHEMBL4031509 | 0.77 | PTGS1 (1.00) | PTGS1P2RX1GAAAHRHSD17B10 | |
| SCHEMBL29392990 | 0.77 | PTGS1 (1.00) | PTGS1P2RX1GAAAHRHSD17B10 | |
| SCHEMBL27548630 | 0.76 | PTGS1 (0.63) | PTGS1P2RX1GAAAHRHSD17B10 | |
| SCHEMBL3110637 | 0.75 | KDR (0.66) | PTGS1RXFP1 | |
| SCHEMBL27486253 | 0.75 | PTGS1 (0.58) | PTGS1P2RX1GAAAHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633336-B1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | NOVARTIS AG (CH) | 2016-06-22 | — | — | EP | claimed |
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | claimed |