Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 13/20 | 0.53 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466657 | 0.82 | PTGS1 (0.64) | PTGS1RXFP1P2RX1GAAAHR | |
| SCHEMBL27483851 | 0.82 | PTGS1 (0.60) | PTGS1MAPTRXFP1DDR2P2RX1 | |
| SCHEMBL17836886 | 0.81 | PTGS1 (0.61) | PTGS1RXFP1P2RX1GAAAHR | |
| SCHEMBL1011471 | 0.80 | RXFP1 (0.80) | RXFP1DDR2 | |
| SCHEMBL31424184 | 0.77 | PTGS1 (1.00) | PTGS1MAPTRXFP1P2RX1GAA | |
| SCHEMBL4031509 | 0.77 | PTGS1 (1.00) | PTGS1MAPTRXFP1P2RX1GAA | |
| SCHEMBL29392990 | 0.77 | PTGS1 (1.00) | PTGS1MAPTRXFP1P2RX1GAA | |
| SCHEMBL27486253 | 0.77 | PTGS1 (0.58) | PTGS1RXFP1P2RX1GAAAHR | |
| SCHEMBL11308212 | 0.76 | PTGS1 (0.78) | PTGS1MAPTRXFP1P2RX1GAA | |
| SCHEMBL27548630 | 0.76 | PTGS1 (0.63) | PTGS1MAPTRXFP1P2RX1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1578768-A | Anthranilamides and pharmaceutical use thereof | NOVARTIS AG (CH) | 2005-02-09 | — | — | CN | claimed |
| CN-100467450-C | Anthranilamides and pharmaceutical use thereof | NOVARTIS AG (CH) | 2009-03-11 | — | — | CN | disclosed |
| CN-1578768-A | Anthranilamides and pharmaceutical use thereof | NOVARTIS AG (CH) | 2005-02-09 | — | — | CN | disclosed |