⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12657248 | 0.85 | GAA (0.36) | — | |
| SCHEMBL4291847 | 0.82 | — | — | |
| SCHEMBL4199013 | 0.75 | GAA (0.41) | — | |
| SCHEMBL5392067 | 0.74 | — | — | |
| SCHEMBL1235274 | 0.73 | GAA (0.36) | — | |
| SCHEMBL1235273 | 0.73 | GAA (0.36) | — | |
| SCHEMBL5399357 | 0.72 | — | — | |
| SCHEMBL1171891 | 0.72 | — | — | |
| SCHEMBL1052043 | 0.69 | — | — | |
| SCHEMBL3951114 | 0.69 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114947175-A | Composition for simulating tobacco flavor | 尼科创业贸易有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-109906042-B | Composition for simulating tobacco flavor | 尼科创业贸易有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-9550765-B2 | Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2017-01-24 | — | — | US | disclosed |
| EP-2719698-B1 | Methods for preparing aurora kinase inhibitors | MILLENNIUM PHARM INC (US) | 2016-10-05 | — | — | EP | disclosed |
| US-9200004-B2 | Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150329534-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION | 2015-11-19 | — | — | US | disclosed |
| US-20140200227-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2014-07-17 | — | — | US | disclosed |
| US-8450533-B2 | Cyclopropanation process | GIVAUDAN SA (CH) | 2013-05-28 | — | — | US | disclosed |
| US-8450533-B2 | Cyclopropanation process | GIVAUDAN SA (CH) | 2013-05-28 | — | — | US | disclosed |
| US-8450533-B2 | Cyclopropanation process | GIVAUDAN SA (CH) | 2013-05-28 | — | — | US | disclosed |
| EP-2261226-A1 | Compounds and methods for inhibiting mitotic progression by inhibition of aurora kinase | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-2190803-A1 | CYCLOPROPANATION PROCESS | Givaudan SA (CH) | 2010-06-02 | — | — | EP | disclosed |
| US-7598417-B2 | Analgesics; muscular disorders; diarrhea | ALLERGAN, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| WO-2009023980-A1 | CYCLOPROPANATION PROCESS | GIVAUDAN SA (CH) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009023980-A1 | CYCLOPROPANATION PROCESS | GIVAUDAN SA (CH) | 2009-02-26 | — | — | WO | disclosed |
| US-20080255239-A1 | SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS | ALLERGAN, INC. | 2008-10-16 | — | — | US | disclosed |
| US-4315032-A | ANTITHROMBOGENIC AGENTS, ANTIULCER AGENTS | TEITIN LIMITED (JP) | 1982-02-09 | — | — | US | disclosed |
| EP-0019475-A2 | Process for preparing adjacently disubstituted ketones, novel prostaglandins E1 and anti-thrombotic compositions containing them | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | disclosed |
| US-4139717-A | 1,3-Dicarbonyl compounds | TEIJIN LIMITED (JP) | 1979-02-13 | — | — | US | disclosed |
| US-4009196-A | HYPOTENSIVE AGENTS, BRONCHODILATORS, PROSTAGLANDIN ANALOGS | TEIJIN LIMITED (JA) | 1977-02-22 | — | — | US | disclosed |