Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TYMP | P19971 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021820 | 0.79 | SCD (0.40) | SCDALDH1A1TDP1MAPTTHRB | |
| SCHEMBL7187409 | 0.79 | SCD (0.40) | SCDALDH1A1TDP1MAPTTHRB | |
| SCHEMBL25269553 | 0.77 | ALDH1A1 (0.33) | GAAALDH1A1TDP1MAPTTHRB | |
| SCHEMBL2335039 | 0.77 | SCD (0.46) | SCDALDH1A1THRBACHELMNA | |
| SCHEMBL9340336 | 0.74 | SCD (0.50) | SCDALDH1A1THRBACHELMNA | |
| SCHEMBL4441878 | 0.73 | ALDH1A1 (0.39) | SCDALDH1A1TDP1MAPTTHRB | |
| SCHEMBL1022312 | 0.72 | SCD (0.33) | GAASCD | |
| SCHEMBL5390508 | 0.71 | HTT (0.34) | SCDALDH1A1CYP1A2 | |
| SCHEMBL11759188 | 0.71 | SCD (0.36) | SCDALDH1A1TDP1MAPTALOX5 | |
| SCHEMBL114204 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPTTHRBTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069513-A2 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | California Institute of Technology (US) | 2009-06-17 | — | — | EP | disclosed |
| US-7544826-B2 | Monocyclopentadienyl complexes | BASELL POLYOLEFINE GMBH (DE) | 2009-06-09 | — | — | US | disclosed |
| EP-1694689-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008016709-A2 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | WO | disclosed |
| US-20070213484-A1 | Monocyclopentadienyl Complexes | BASELL POLYOLEFINE GMBH (DE) | 2007-09-13 | — | — | US | disclosed |
| EP-1694689-A1 | MONOCYCLOPENTADIENYL COMPLEXES | Basell Polyolefine GmbH (DE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058928-A1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213484-A1 | Monocyclopentadienyl Complexes | PCBP1, COASY, PORCN | GAA 4630/4885SCD 25/4885ALDH1A1 2691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.