SCHEMBL1783719

SCHEMBL1783719

CN1c2ccccc2Nc2cc(N)ccc21.COS(=O)(=O)O

nearest known ligand 0.41

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 known ✓ P20309 1/20 0.40
CHEK1 O14757 2/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
NOX1 Q9Y5S8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
SLC6A2 P23975 1/20 0.40
HTR2C P28335 1/20 0.40
SLC6A4 P31645 1/20 0.40
DRD3 P35462 1/20 0.40
HTR2B P41595 1/20 0.40
GAA P10253 4/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
AURKA O14965 1/20 0.38
DAPK3 O43293 1/20 0.38
JAK2 O60674 1/20 0.38
PRKD3 O94806 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL29203961 0.92 MEN1 (0.44) CHEK1MEN1KMT2ANOX1L3MBTL1
SCHEMBL30823916 0.87 GAA (0.47) CHEK1KMT2AGAASMN1; SMN2KDM4E
SCHEMBL196642 0.87 GAA (0.47) CHEK1KMT2AGAASMN1; SMN2KDM4E
SCHEMBL29414570 0.87 GAA (0.47) CHEK1KMT2AGAASMN1; SMN2KDM4E
SCHEMBL30136337 0.86 KMT2A (0.51) CHEK1MEN1KMT2ANOX1L3MBTL1
Sulfuric Acid SCHEMBL8008464 0.78 GAA (0.53) CHEK1KMT2AGAASMN1; SMN2MAPT
SCHEMBL9644871 0.77 GAA (0.44) CHEK1KMT2AGAASMN1; SMN2KDM4E
SCHEMBL2490578 0.77 CHEK1 (0.42) CHEK1MEN1KMT2ADRD3GAA
SCHEMBL31398538 0.77 CHEK1 (0.42) CHEK1MEN1KMT2ADRD3GAA
SCHEMBL4417312 0.76 SMN1; SMN2 (0.42) CHEK1KMT2AGAASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140024102-A1 MICROBIAL FUEL CELL, FUEL AND MICROBES FOR SAID FUEL CELL, BIOREACTOR AND BIOSENSOR SONY CORPORATION 2014-01-23 US disclosed
US-8338039-B2 Fuel cell SONY CORPORATION (JP) 2012-12-25 US disclosed
US-20110287312-A1 BIOFUEL CELL SONY CORPORATION (JP) 2011-11-24 US disclosed
US-20110250511-A1 BIOFUEL CELL SONY CORPORATION (JP) 2011-10-13 US disclosed
US-20110143223-A1 FUEL CELL SONY CORPORATION (JP) 2011-06-16 US disclosed
US-20110117453-A1 FUEL REFORMER AND POWER GENERATION APPARATUS USING THE SAME SONY CORPORATION (JP) 2011-05-19 US disclosed