Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 6/20 | 0.33 |
| ▸ | GABRD | O14764 | 6/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.33 |
| ▸ | GABRE | P78334 | 6/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785655 | 0.93 | PTGS1 (0.35) | PTGS1UGT2B7GABRPGABRDGABRA1 | |
| SCHEMBL14192659 | 0.93 | PTGS1 (0.35) | PTGS1UGT2B7GABRPGABRDGABRA1 | |
| SCHEMBL23364672 | 0.81 | SLC1A2 (0.42) | UGT2B7GMNNLMNABLMPMP22 | |
| Acetic Acid SCHEMBL6561255 | 0.81 | SLC1A2 (0.38) | PTGS1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2841706 | 0.79 | EPHX1 (0.35) | UGT2B7 | |
| SCHEMBL10793287 | 0.79 | EPHX1 (0.35) | UGT2B7 | |
| SCHEMBL2844101 | 0.79 | EPHX1 (0.35) | UGT2B7 | |
| SCHEMBL28003101 | 0.76 | GAA (0.35) | UGT2B7LMNA | |
| SCHEMBL11708816 | 0.76 | ATM (0.41) | KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14375557 | 0.76 | ATM (0.41) | KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | PTGS1 593/4885UGT2B7 3160/4885GABRP 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.