Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18531572 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 | |
| SCHEMBL788457 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 | |
| SCHEMBL1783889 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 | |
| SCHEMBL20942874 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 | |
| SCHEMBL20942892 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 | |
| SCHEMBL20942870 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 | |
| SCHEMBL20942872 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 | |
| SCHEMBL20942871 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 | |
| SCHEMBL20942893 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 | |
| SCHEMBL788458 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CES2CES1TRPA1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2703407-B1 | METHOD FOR MANUFACTURING PHOSPHONOCROTONIC ACID DERIVATIVE | KOWA CO (JP) | 2017-07-26 | — | — | EP | claimed |
| US-9540301-B2 | Method for manufacturing phosphonocrotonic acid derivative | KOWA COMPANY, LTD. (JP) | 2017-01-10 | — | — | US | claimed |
| EP-2703407-A1 | METHOD FOR MANUFACTURING PHOSPHONOCROTONIC ACID DERIVATIVE | Kowa Company, Ltd. (JP) | 2014-03-05 | — | — | EP | claimed |
| US-20140051876-A1 | METHOD FOR MANUFACTURING PHOSPHONOCROTONIC ACID DERIVATIVE | MANAC INCORPORATED (JP) | 2014-02-20 | — | — | US | claimed |
| US-20080311175-A1 | Compositions and Methods for Promoting Weight Gain and Feed Conversion | CHEMAPHOR, INC. (CA) | 2008-12-18 | — | — | US | claimed |
| EP-1806982-A4 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT GAIN AND FEED CONVERSION | CHEMAPHOR INC (CA) | 2008-03-19 | — | — | EP | claimed |
| EP-1806982-A1 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT GAIN AND FEED CONVERSION | Chemaphor Inc. (CA) | 2007-07-18 | — | — | EP | claimed |
| WO-2006034570-A1 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT GAIN AND FEED CONVERSION | CHEMAPHOR INC. (CA) | 2006-04-06 | — | — | WO | claimed |
| EP-0430808-B1 | Dihydropyran derivatives, their processes of preparation and their use | RHONE POULENC NUTRITION ANIMAL (FR) | 1995-03-29 | — | — | EP | claimed |
| EP-0430807-A1 | Process for the preparation of halogeno-acetals from enamines | RHONE-POULENC NUTRITION ANIMALE (FR) | 1991-06-05 | — | — | EP | claimed |
| EP-0430808-A1 | Dihydropyran derivatives, their processes of preparation and their use | RHONE-POULENC NUTRITION ANIMALE (FR) | 1991-06-05 | — | — | EP | claimed |
| CN-111499662-B | Isotretinoin C15-triphenylphosphine chloride and preparation method and application thereof | 上海新华联制药有限公司 | 2022-12-20 | — | — | CN | disclosed |
| US-11291947-B2 | Composition for removing sulfur-containing compound | KURARAY CO., LTD. (JP) | 2022-04-05 | — | — | US | disclosed |
| US-20190329175-A1 | COMPOSITION FOR REMOVING SULFUR-CONTAINING COMPOUND | KURARAY CO., LTD. (JP) | 2019-10-31 | — | — | US | disclosed |
| US-10449247-B2 | Compositions and methods for enhancing immune response | AVIVAGEN INC. (CA) | 2019-10-22 | — | — | US | disclosed |
| EP-0430806-A1 | Process for the preparation of haloketals from enamines | RHONE-POULENC NUTRITION ANIMALE (FR) | 1991-06-05 | — | — | EP | disclosed |
| EP-0430807-A1 | Process for the preparation of halogeno-acetals from enamines | RHONE-POULENC NUTRITION ANIMALE (FR) | 1991-06-05 | — | — | EP | disclosed |
| EP-0430808-A1 | Dihydropyran derivatives, their processes of preparation and their use | RHONE-POULENC NUTRITION ANIMALE (FR) | 1991-06-05 | — | — | EP | disclosed |
| US-3989758-A | Monoacetals of unsaturated aliphatic dialdehydes | HOFFMANN-LA ROCHE INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3974181-A | Trimethyl-1,4-dioxaspiro[4,5]dec-7-en-8-methanol | HOFFMANN-LA ROCHE INC. (US) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051876-A1 | METHOD FOR MANUFACTURING PHOSPHONOCROTONIC ACID DERIVATIVE | C1S, C3AR1, C9 | ALDH1A1 1492/4885CES2 2825/4885CES1 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.