SCHEMBL1783922

SCHEMBL1783922

CC1=CC[C@H](C[C@@H]2C[C@@]2(C)CO)C1(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2986880 1.00 USP2 (0.36) USP2NPSR1
SCHEMBL2986881 1.00 USP2 (0.36) USP2NPSR1
SCHEMBL1783918 1.00 USP2 (0.36) USP2NPSR1
SCHEMBL8462040 0.87 USP2 (0.35) USP2NPSR1
SCHEMBL21964082 0.78 F10 (0.35) USP2NPSR1
SCHEMBL28581142 0.78 USP2 (0.32) USP2NPSR1
SCHEMBL7784061 0.78 USP2 (0.35) USP2NPSR1
SCHEMBL12611338 0.78 USP2 (0.35) USP2NPSR1
SCHEMBL7784007 0.74 USP2 (0.35) USP2NPSR1
SCHEMBL13206360 0.73 USP2 (0.40) USP2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450533-B2 Cyclopropanation process GIVAUDAN SA (CH) 2013-05-28 US disclosed
US-20110124924-A1 Cyclopropanation Process GIVAUDAN SA (CH) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124924-A1 Cyclopropanation Process CBR3, CYP4F3, DBF4 USP2 2581/4885NPSR1 4224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.