⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645216 | 0.97 | HIF1A (0.47) | — | |
| SCHEMBL2747826 | 0.97 | HIF1A (0.47) | — | |
| SCHEMBL6565722 | 0.97 | HIF1A (0.47) | — | |
| SCHEMBL231505 | 0.97 | HIF1A (0.47) | — | |
| SCHEMBL22657401 | 0.97 | HIF1A (0.47) | — | |
| SCHEMBL28092393 | 0.97 | HIF1A (0.47) | — | |
| SCHEMBL29135628 | 0.92 | HIF1A (0.43) | — | |
| SCHEMBL1784550 | 0.92 | TSHR (0.48) | — | |
| SCHEMBL1783238 | 0.89 | TSHR (0.52) | — | |
| SCHEMBL12189609 | 0.89 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2020-09-29 | — | — | US | claimed |
| US-20190177366-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | GENENTECH, INC. (US) | 2019-06-13 | — | — | US | claimed |
| EP-2277599-B1 | Reductive colour removal | HENKEL AG & CO KGAA (DE) | 2019-01-23 | — | — | EP | claimed |
| WO-2024054840-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-115043963-A | High-solid-content polyvinylidene fluoride dispersion liquid and preparation method and application thereof | 万华化学(四川)电池材料科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113666955-A | Novel stable silylating agents | 加州理工学院 | 2021-11-19 | — | — | CN | disclosed |
| CN-108699089-B | Novel stable silylating agents | 加州理工学院 | 2021-08-03 | — | — | CN | disclosed |
| US-11034725-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-20200283478-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | GENENTECH, INC. (US) | 2020-09-10 | — | — | US | disclosed |
| US-6040465-A | Process for producing optically active β-lactones | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-03-21 | — | — | US | disclosed |
| US-5998635-A | CATALYTIC CYCLIZATION AN ALDEHYDE WITH A KETENE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-12-07 | — | — | US | disclosed |
| US-5962002-A | 1,1,4,4-SUBSTITUTED DIHYDRONAPHTHALENE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| EP-0802730-B1 | PESTICIDAL COMPOUNDS | BTG INT LTD (GB) | 1999-06-23 | — | — | EP | disclosed |
| CN-1177906-A | Pesticidal compounds | BRITISH TECH GROUP (GB) | 1998-04-01 | — | — | CN | disclosed |
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0583971-A1 | Piperidine derivatives | SANKYO COMPANY LIMITED (JP) | 1994-02-23 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |