SCHEMBL28645216 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	HIF1A	Q16665	1/20	0.47

▸	TSHR	P16473	2/20	0.46

▸	FAAH	O00519	2/20	0.37

▸	TRPV1	Q8NER1	2/20	0.37

▸	ALDH1A1	P00352	1/20	0.36

▸	MAPT	P10636	1/20	0.33

▸	ACLY	P53396	1/20	0.32

▸	TDP1	Q9NUW8	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1784079	0.97	—	—
SCHEMBL28092393	0.94	HIF1A (0.47)	HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL22657401	0.94	HIF1A (0.47)	HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL2747826	0.94	HIF1A (0.47)	HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL231505	0.94	HIF1A (0.47)	HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL6565722	0.94	HIF1A (0.47)	HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL29135628	0.90	HIF1A (0.43)	HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL1784550	0.89	TSHR (0.48)	HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL16491137	0.86	TSHR (0.52)	HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL12189609	0.86	TSHR (0.52)	HIF1ATSHRFAAHTRPV1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110423239-B	1, 3-oxazine 1,2, 3-triazole derivative and synthetic method and application thereof	昆明理工大学	2021-10-26	—	—	CN	disclosed