⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9731497 | 0.97 | — | — | |
| SCHEMBL19606415 | 0.85 | KDM4E (0.40) | — | |
| SCHEMBL18551591 | 0.85 | KDM4E (0.40) | — | |
| SCHEMBL21839006 | 0.85 | KDM4E (0.40) | — | |
| SCHEMBL12371246 | 0.85 | KDM4E (0.40) | — | |
| SCHEMBL25129088 | 0.85 | KDM4E (0.40) | — | |
| SCHEMBL22861638 | 0.85 | KDM4E (0.40) | — | |
| SCHEMBL2738332 | 0.85 | L3MBTL1 (0.39) | — | |
| SCHEMBL3400008 | 0.83 | — | — | |
| SCHEMBL8262524 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897778-B2 | Benzamide compounds | ASTRAZENECA (SE) | 2011-03-01 | — | — | US | claimed |
| US-20080293687-A1 | Benzamide Compounds | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | claimed |
| JP-2215751-A | — | — | None | — | — | JP | disclosed |
| JP-2214705-A | — | — | None | — | — | JP | disclosed |
| WO-2025224168-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-10-30 | — | — | WO | disclosed |
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |
| US-20240400564-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | SYNDAX PHARMACEUTICALS, INC. | 2024-12-05 | — | — | US | disclosed |
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | ARVINAS OPERATIONS, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| CN-117956992-A | MENIN-MLL interaction inhibitors | 赛达克斯制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| US-20240109917-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2024-04-04 | — | — | US | disclosed |
| US-5869500-A | INHIBITING BETA-AMYLOID PEPTIDE ACTIVITY | HOFFMANN-LA ROCHE INC. (US) | 1999-02-09 | — | — | US | disclosed |
| US-5824678-A | TREATMENT OF PAIN, INFLAMMATION, MIGRAINE, EMESIS; PREPARATION THEREOF | MERCK SHARP & DOHME LTD. (GB) | 1998-10-20 | — | — | US | disclosed |
| WO-1998025930-A2 | USE OF BI- AND TRICYCLIC PYRIDONE DERIVATIVES AGAINST ALZHEIMER'S DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 1998-06-18 | — | — | WO | disclosed |
| WO-1997022589-A1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LIMITED (GB) | 1997-06-26 | — | — | WO | disclosed |
| EP-0777659-A1 | MORPHOLINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005181-A1 | MORPHOLINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |
| US-5162582-A | Molding materials | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1992-11-10 | — | — | US | disclosed |
| JP-H02215751-A | NEW VINYL COMPOUND | AGENCY OF IND SCIENCE & TECHNOL | 1990-08-28 | — | — | JP | disclosed |
| JP-H02214705-A | HYDROPHILIC-HYDROPHOBIC THERMALLY REVERSIBLE POLYMERIC COMPOUND AND PRODUCTION THEREOF | AGENCY OF IND SCIENCE & TECHNOL | 1990-08-27 | — | — | JP | disclosed |