Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844213 | 0.90 | NR1H2 (0.37) | NR1H2NR1H3BCHEACHERIPK1 | |
| SCHEMBL2004351 | 0.86 | NR1H2 (0.52) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL1997567 | 0.81 | NR1H2 (0.55) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL1999995 | 0.79 | NR1H2 (0.49) | NR1H2NR1H3ACHELMNAMEN1 | |
| SCHEMBL1998440 | 0.78 | NR1H2 (0.48) | NR1H2NR1H3BCHEACHELMNA | |
| SCHEMBL2001035 | 0.78 | NR1H2 (0.48) | NR1H2NR1H3PKMNPC1ALDH1A1 | |
| SCHEMBL1999147 | 0.77 | NR1H2 (0.47) | NR1H2NR1H3BCHEACHELMNA | |
| SCHEMBL1995172 | 0.76 | NR1H2 (0.52) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL1998211 | 0.76 | ACHE (0.57) | NR1H2NR1H3BCHEACHELMNA | |
| SCHEMBL2004349 | 0.76 | NR1H2 (0.40) | NR1H2NR1H3BCHEACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |