Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000830 | 0.85 | NR1H2 (0.49) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL2000304 | 0.82 | NR1H2 (0.48) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL1999381 | 0.80 | NR1H2 (0.45) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL2002953 | 0.79 | NR1H2 (0.47) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL2000018 | 0.78 | NR1H2 (0.45) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL1999973 | 0.78 | NR1H2 (0.45) | NR1H2NR1H3 | |
| SCHEMBL1998235 | 0.78 | NR1H2 (0.51) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL2004213 | 0.78 | NR1H2 (0.43) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL1999833 | 0.78 | NR1H2 (0.43) | NR1H2NR1H3CA12CA2CA9 | |
| SCHEMBL2002288 | 0.78 | CHRNB2 (0.44) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |