Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | YAP1 | P46937 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431949 | 0.85 | PDE4A (0.57) | KDM4EPKMSLC2A1GPR119CSF1R | |
| SCHEMBL17835708 | 0.83 | KDM4E (0.48) | KDM4EPKMSLC2A1GPR119CSF1R | |
| SCHEMBL29992791 | 0.77 | SLC2A1 (0.56) | KDM4EPKMSLC2A1GPR119CSF1R | |
| SCHEMBL15996233 | 0.77 | SLC2A1 (0.56) | KDM4EPKMSLC2A1GPR119CSF1R | |
| SCHEMBL19610219 | 0.77 | GPR119 (0.45) | KDM4EPKMSLC2A1GPR119CSF1R | |
| SCHEMBL21473562 | 0.77 | PDE4B (0.56) | KDM4EPKMSLC2A1GPR119STS | |
| SCHEMBL1056543 | 0.77 | PDE4B (0.54) | KDM4EPKMSLC2A1GPR119STS | |
| SCHEMBL30015882 | 0.77 | PDE4B (0.56) | KDM4EPKMSLC2A1GPR119STS | |
| SCHEMBL2129649 | 0.77 | GPR119 (0.57) | KDM4EPKMGPR119PDE4APDE4B | |
| SCHEMBL65285 | 0.77 | GPR119 (0.59) | KDM4EPKMSLC2A1GPR119CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233847-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GenKyoTex Suisse SA (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016098005-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2016-06-23 | — | — | WO | disclosed |