Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844662 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL17844569 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL17844580 | 0.76 | KDM4E (0.72) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL17844558 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL17844559 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL6224291 | 0.70 | ACLY (0.47) | TSHRMEN1KMT2AAHRACLY | |
| SCHEMBL6890851 | 0.69 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2GCGRMAPT | |
| SCHEMBL6227928 | 0.68 | ACLY (0.45) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL6225252 | 0.68 | PPARG (0.47) | KDM4ELMNAACLYHSD17B10 | |
| SCHEMBL10603520 | 0.68 | GCGR (0.43) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016096942-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-23 | — | — | WO | disclosed |