Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088026 | 0.73 | HSD17B2 (0.45) | PYGLKDM4EHPGDHSD17B10LMNA | |
| SCHEMBL17844580 | 0.73 | KDM4E (0.72) | KDM4EALDH1A1GAARXFP1SMN1; SMN2 | |
| SCHEMBL17844558 | 0.72 | KDM4E (0.51) | KDM4EALDH1A1GAARXFP1SMN1; SMN2 | |
| SCHEMBL17748297 | 0.70 | MAPK1 (0.58) | PYGLKDM4EALDH1A1GAAHPGD | |
| SCHEMBL22573639 | 0.68 | NPC1 (0.47) | PYGLKDM4EALDH1A1GAARXFP1 | |
| SCHEMBL16627663 | 0.67 | SMYD3 (0.53) | KDM4EALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL6463167 | 0.67 | ALAD (0.55) | PYGLKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8663770 | 0.66 | MAPT (0.54) | KDM4EALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL8288031 | 0.66 | NPC1 (0.70) | ALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL1547993 | 0.66 | KDM4E (0.55) | KDM4EALDH1A1GAARXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016096942-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-23 | — | — | WO | disclosed |