Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F11 | P03951 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844727 | 0.77 | F2 (0.34) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL17844718 | 0.77 | MCL1 (0.34) | — | |
| SCHEMBL16345882 | 0.76 | F2 (0.35) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL17844720 | 0.75 | F2 (0.34) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL19742277 | 0.75 | F2 (0.34) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL21871238 | 0.72 | TRPA1 (0.37) | PDGFRBKDRLIPG | |
| SCHEMBL19742268 | 0.71 | F2 (0.33) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL19750049 | 0.71 | F2 (0.33) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL17859529 | 0.71 | PRMT5 (0.44) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL4162207 | 0.70 | F2 (0.44) | F2F11PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369470-A1 | Cyclic Compounds and Uses Thereof | Karyopharm Therapeutics Inc. | 2017-12-28 | — | — | US | disclosed |
| WO-2016100515-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Karyopharm Therapeutics Inc. (US) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369470-A1 | Cyclic Compounds and Uses Thereof | MALT1, BCL9, BCL6 | F2 4614/4885F11 3515/4885PRSS1 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.