Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845140 | 0.84 | TNK2 (0.32) | TNK2CNR1CNR2 | |
| SCHEMBL17845114 | 0.80 | CNR1 (0.35) | CNR1CNR2 | |
| SCHEMBL17845093 | 0.79 | TNK2 (0.36) | TNK2 | |
| SCHEMBL19125371 | 0.70 | S1PR3 (0.35) | TNK2 | |
| SCHEMBL17845105 | 0.70 | NR1H4 (0.40) | CNR1CNR2 | |
| SCHEMBL12970332 | 0.69 | TNK2 (0.43) | TNK2 | |
| SCHEMBL17845087 | 0.68 | TNK2 (0.39) | TNK2 | |
| SCHEMBL17845094 | 0.67 | PTGS1 (0.38) | TNK2 | |
| SCHEMBL5863927 | 0.67 | HPGD (0.40) | TNK2 | |
| SCHEMBL15441837 | 0.63 | ALDH1A1 (0.54) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233828-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | F. Hoffmann-La Roche AG (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097071-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2016-06-23 | — | — | WO | disclosed |