Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180453 | 0.83 | MAPT (0.73) | MAPTHTTSMN1; SMN2GAADNM1 | |
| SCHEMBL9015860 | 0.80 | MAPT (0.68) | MAPTHTTSMN1; SMN2KDM4EDNM1 | |
| SCHEMBL20788755 | 0.80 | MAPT (0.63) | MAPTHTTSMN1; SMN2DNM1ABCB1 | |
| SCHEMBL7277860 | 0.78 | MAPT (0.68) | MAPTHTTSMN1; SMN2KDM4EDNM1 | |
| SCHEMBL23386838 | 0.78 | KDM4E (0.50) | KDM4EDNM1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL28335665 | 0.77 | MAPT (0.59) | MAPTHTTSMN1; SMN2GAAKDM4E | |
| SCHEMBL29430333 | 0.77 | MAPT (0.63) | MAPTHTTSMN1; SMN2GAADNM1 | |
| SCHEMBL3083085 | 0.76 | MAPT (0.57) | MAPTHTTSMN1; SMN2GAADNM1 | |
| SCHEMBL11448213 | 0.76 | MAPT (0.93) | MAPTHTTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31010245 | 0.75 | MAPT (0.56) | MAPTHTTSMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016098128-A1 | PROCESS FOR THE PREPARATION OF BEPRIDIL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016098128-A1 | PROCESS FOR THE PREPARATION OF BEPRIDIL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-23 | — | — | WO | disclosed |