Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180453 | 0.87 | MAPT (0.73) | MAPTHTTSMN1; SMN2DNM1ABCB1 | |
| SCHEMBL29430333 | 0.80 | MAPT (0.63) | MAPTHTTSMN1; SMN2DNM1LMNA | |
| SCHEMBL17845180 | 0.80 | MAPT (0.68) | MAPTHTTSMN1; SMN2DNM1ABCB1 | |
| SCHEMBL20788755 | 0.80 | MAPT (0.63) | MAPTHTTSMN1; SMN2DNM1ABCB1 | |
| SCHEMBL7277860 | 0.78 | MAPT (0.68) | MAPTHTTSMN1; SMN2DNM1ABCB1 | |
| SCHEMBL9165276 | 0.78 | DNM1 (0.48) | DNM1ADRB2ADRB1BCHEMEN1 | |
| SCHEMBL22584806 | 0.77 | MAPT (0.59) | MAPTHTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7346554 | 0.77 | MAPT (0.58) | MAPTHTTSMN1; SMN2DNM1ABCB1 | |
| SCHEMBL1298434 | 0.76 | MAPT (0.61) | MAPTHTTSMN1; SMN2DNM1ADRB2 | |
| SCHEMBL11448213 | 0.76 | MAPT (0.93) | MAPTHTTSMN1; SMN2ABCB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| US-5122244-A | Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |