SCHEMBL17845285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17845557	0.82	PARG (0.53)	PARGKDM4EALDH1A1MEN1TP53
	SCHEMBL17845645	0.81	PARG (0.47)	PARGALDH1A1TP53
	SCHEMBL31122085	0.79	PARG (0.60)	PARGKDM4EALDH1A1MEN1HPGD
	SCHEMBL17845291	0.77	PARG (0.59)	PARGKDM4EALDH1A1MEN1KMT2A
	SCHEMBL17845644	0.74	PARG (0.53)	PARGPGRKDM4EALDH1A1HPGD
	SCHEMBL17845326	0.74	PARG (0.53)	PARGPGRKDM4EALDH1A1MEN1
	SCHEMBL31121978	0.74	AURKA (0.51)	KDM4EMEN1KMT2AHSD17B10CYP1A2
	SCHEMBL20170438	0.70	PIK3CA (0.42)	PGRKDM4EALDH1A1L3MBTL1MEN1
	SCHEMBL13156259	0.69	PTGER1 (0.53)	CYP1A2
	SCHEMBL29798837	0.68	CYP1A2 (0.55)	PGRKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.