SCHEMBL17845557

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17845285	0.82	PARG (0.54)	PARGMEN1KMT2ATP53KDM4E
	SCHEMBL17845486	0.77	PARG (0.52)	PARG
	SCHEMBL17845645	0.75	PARG (0.47)	PARGTP53ALDH1A1
	SCHEMBL17845719	0.72	PARG (0.55)	PARG
	SCHEMBL31650745	0.71	SMN1; SMN2 (0.55)	MAPK14TP53PKMSMN1; SMN2KDM4E
	SCHEMBL13355033	0.71	SMN1; SMN2 (0.55)	MAPK14TP53PKMSMN1; SMN2KDM4E
	SCHEMBL17845419	0.70	PARG (0.53)	PARGMAPK14MEN1HCRTR1KMT2A
	SCHEMBL31121949	0.70	PARG (0.53)	PARGMAPK14MEN1HCRTR1KMT2A
	SCHEMBL17845463	0.70	PARG (1.00)	PARG
	SCHEMBL31122004	0.70	PARG (1.00)	PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.