SCHEMBL1784530

SCHEMBL1784530

CCCC(OC(=O)c1ccccc1)C(C)(C)OC(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C19 P33261 1/20 0.51
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
LMNA P02545 3/20 0.46
TSHR P16473 3/20 0.45
TP53 P04637 1/20 0.45
PRSS1 P07477 2/20 0.44
CTSG P08311 2/20 0.44
CTRB1 P17538 2/20 0.44
CMA1 P23946 2/20 0.44
TDP1 Q9NUW8 2/20 0.43
HTR1A P08908 1/20 0.43
SCN1A P35498 1/20 0.43
SLC6A3 Q01959 1/20 0.43
SCN5A Q14524 1/20 0.43
SCN2A Q99250 1/20 0.43
SCN3A Q9NY46 1/20 0.43
ALDH1A1 P00352 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1786952 0.88 MEN1 (0.51) CYP2D6CYP1A2CYP2C19MEN1KMT2A
SCHEMBL1784502 0.88 CYP2D6 (0.54) CYP2D6CYP1A2CYP2C19MEN1KMT2A
SCHEMBL1784701 0.84 MEN1 (0.48) CYP2D6CYP1A2CYP2C19MEN1KMT2A
SCHEMBL1787176 0.83 KMT2A (0.50) CYP2D6CYP1A2CYP2C19MEN1KMT2A
SCHEMBL1789328 0.83 LMNA (0.47) CYP2D6CYP1A2CYP2C19MEN1KMT2A
SCHEMBL1786784 0.82 CYP1A2 (0.51) CYP2D6CYP1A2CYP2C19MEN1KMT2A
SCHEMBL1784794 0.82 LMNA (0.46) CYP2D6CYP1A2CYP2C19MEN1KMT2A
SCHEMBL1783513 0.81 MEN1 (0.46) CYP2D6CYP1A2CYP2C19MEN1KMT2A
Benzoic Acid SCHEMBL19991298 0.79 CYP2D6 (0.49) CYP2D6CYP1A2CYP2C19MEN1KMT2A
SCHEMBL1788292 0.79 MEN1 (0.44) CYP2D6CYP1A2CYP2C19MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
EP-2185600-B1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE GRACE W R & CO (US) 2018-10-31 EP disclosed
US-9796796-B2 Self-limiting catalyst composition with No silane W. R. GRACE & CO.-CONN. (US) 2017-10-24 US disclosed
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110124491-A1 Self-Limiting Catalyst Composition with No Silane W. R. GRACE & CO.-CONN. 2011-05-26 US disclosed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed