Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845421 | 0.89 | PARG (0.57) | PARG | |
| SCHEMBL17845616 | 0.82 | PARG (0.65) | PARG | |
| SCHEMBL17845675 | 0.81 | PARG (0.56) | PARG | |
| SCHEMBL17845524 | 0.80 | PARG (0.58) | PARG | |
| SCHEMBL17845450 | 0.78 | PARG (0.62) | PARG | |
| SCHEMBL17845656 | 0.73 | PARG (1.00) | PARG | |
| SCHEMBL17845267 | 0.70 | PARG (1.00) | PARG | |
| SCHEMBL31481878 | 0.69 | PARG (0.71) | PARG | |
| SCHEMBL17845504 | 0.69 | PARG (0.58) | PARG | |
| SCHEMBL17845513 | 0.69 | PARG (1.00) | PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233845-A1 | PARG INHIBITORY COMPOUNDS | Cancer Research Technology Limited (GB) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097749-A1 | PARG INHIBITORY COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |