SCHEMBL17845461

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31121991	1.00	PARG (0.65)	PARGKMT2ALMNAPKMKDM4E
	SCHEMBL1820571	0.83	KMT2A (0.65)	KMT2ALMNAPKMKDM4EALDH1A1
	SCHEMBL18391775	0.82	KMT2A (0.64)	KMT2ALMNAPKMKDM4EALDH1A1
	SCHEMBL1803594	0.80	ALDH1A1 (0.67)	KMT2ALMNAPKMKDM4EALDH1A1
	SCHEMBL31121979	0.79	PARG (1.00)	PARGKDM4EHDAC3HDAC4HDAC1
	SCHEMBL17845374	0.79	PARG (1.00)	PARGKDM4EHDAC3HDAC4HDAC1
	SCHEMBL17845347	0.79	PARG (1.00)	PARGKMT2ALMNAPKMKDM4E
	SCHEMBL17845439	0.79	PARG (1.00)	PARGKMT2ALMNAPKMKDM4E
	SCHEMBL1807646	0.78	ALDH1A1 (0.64)	KMT2ALMNAPKMKDM4EALDH1A1
	SCHEMBL14059166	0.78	ALDH1A1 (0.64)	KMT2ALMNAPKMKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.