SCHEMBL17845554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31122085	1.00	PARG (0.60)	PARGHPGDNSD2IDO1CRHBP
	SCHEMBL17845260	0.79	PARG (0.59)	PARGHPGD
	SCHEMBL17845323	0.79	PARG (0.56)	PARGHPGDNSD2IDO1CRHBP
	SCHEMBL17845291	0.79	PARG (0.59)	PARGALDH1A1KDM4ESMN1; SMN2MEN1
	SCHEMBL17845285	0.79	PARG (0.54)	PARGHPGDALDH1A1KDM4EMEN1
	SCHEMBL17845408	0.76	PARG (1.00)	PARG
	SCHEMBL17845434	0.74	PARG (1.00)	PARG
	SCHEMBL17845475	0.73	PARG (0.61)	PARG
	SCHEMBL28909111	0.70	PARG (0.56)	PARG
	SCHEMBL7059524	0.68	GAA (0.49)	HPGDALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.