Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845619 | 0.83 | KMT2A (0.43) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL17845789 | 0.82 | — | — | |
| SCHEMBL17845725 | 0.82 | KDM4E (0.45) | ALDH1A1HPGDSMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL17845614 | 0.82 | GAA (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL17845437 | 0.82 | ALDH1A1 (0.34) | ALDH1A1NPC1HPGDNFKB1RAB9A | |
| SCHEMBL17845563 | 0.82 | ALDH1A1 (0.34) | ALDH1A1NPC1HPGDNFKB1RAB9A | |
| SCHEMBL17845520 | 0.78 | KMT2A (0.39) | KMT2ALMNAMAPTTSHR | |
| SCHEMBL17845760 | 0.78 | ALDH1A1 (0.40) | ALDH1A1NFKB1NFKB2RELASMN1; SMN2 | |
| SCHEMBL17845759 | 0.75 | ALDH1A1 (0.35) | ALDH1A1KMT2AGAAMAPT | |
| SCHEMBL17845655 | 0.74 | TSHR (0.37) | ALDH1A1NPC1HSD17B10KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |