Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15452247 | 0.83 | TYR (0.57) | TYRLMNAADRA1AHTR2BTRPA1 | |
| SCHEMBL27415242 | 0.83 | TYR (0.46) | TYRESR1ADRA2AADRA2BADRA2C | |
| SCHEMBL31618874 | 0.83 | TYR (0.57) | TYRLMNAADRA1AHTR2BTRPA1 | |
| SCHEMBL536338 | 0.83 | TYR (0.46) | TYRESR1ADRA2AADRA2BADRA2C | |
| SCHEMBL950881 | 0.83 | TYR (0.57) | TYRLMNAADRA1AHTR2BTRPA1 | |
| SCHEMBL31618865 | 0.83 | TYR (0.46) | TYRESR1ADRA2AADRA2BADRA2C | |
| SCHEMBL26617178 | 0.79 | TYR (0.40) | TYRESR1ADRA2AADRA2BADRA2C | |
| SCHEMBL5898767 | 0.79 | CA12 (0.40) | TYRESR1ADRA2AADRA2BADRA2C | |
| SCHEMBL27499243 | 0.79 | PDE2A (0.47) | TYRESR1ADRA2AADRA2BADRA2C | |
| SCHEMBL30763516 | 0.77 | LMNA (0.48) | TYRESR1ESR2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11274283-B2 | Method for the enzymatic conversion of a phenol substrate into a corresponding catechol product | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2022-03-15 | — | — | US | disclosed |
| US-20210062164-A1 | METHOD FOR THE ENZYMATIC CONVERSION OF A PHENOL SUBSTRATE INTO A CORRESPONDING CATECHOL PRODUCT | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2021-03-04 | — | — | US | disclosed |
| US-10822594-B2 | Method for the enzymatic conversion of a phenol substrate into a corresponding catechol product | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2020-11-03 | — | — | US | disclosed |
| US-20170355969-A1 | A METHOD FOR THE ENZYMATIC CONVERSION OF A PHENOL SUBSTRATE INTO A CORRESPONDING CATECHOL PRODUCT | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2017-12-14 | — | — | US | disclosed |
| EP-3234164-A1 | A METHOD FOR THE ENZYMATIC CONVERSION OF A PHENOL SUBSTRATE INTO A CORRESPONDING CATECHOL PRODUCT | University College Dublin National University Of Ireland, Dublin (IE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096579-A1 | A METHOD FOR THE ENZYMATIC CONVERSION OF A PHENOL SUBSTRATE INTO A CORRESPONDING CATECHOL PRODUCT | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2016-06-23 | — | — | WO | disclosed |