Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845919 | 1.00 | AKT1 (0.41) | AKT1ALDH1A1CES1CES2TSHR | |
| SCHEMBL2089423 | 0.75 | AKT1 (0.60) | AKT1ALDH1A1TDP1MAPK1RECQL | |
| SCHEMBL4194551 | 0.75 | AKT1 (0.60) | AKT1ALDH1A1TDP1MAPK1RECQL | |
| SCHEMBL10882567 | 0.74 | ATM (0.39) | AKT1ALDH1A1CES1CES2TSHR | |
| SCHEMBL84200 | 0.72 | AKT1 (0.56) | AKT1ALDH1A1CES1CES2TSHR | |
| SCHEMBL9422531 | 0.72 | AKT1 (0.56) | AKT1ALDH1A1CES1CES2TSHR | |
| SCHEMBL3848018 | 0.72 | CYP1B1 (0.61) | ALDH1A1TDP1RECQLMAPTPLIN1 | |
| SCHEMBL3848015 | 0.72 | CYP1B1 (0.61) | ALDH1A1TDP1RECQLMAPTPLIN1 | |
| SCHEMBL496556 | 0.69 | AKT1 (0.46) | AKT1ALDH1A1CES1CES2TSHR | |
| SCHEMBL8522963 | 0.67 | TDP1 (0.39) | ALDH1A1CES1CES2TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237461-A1 | PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES | SABIC Global Technologies B.V. (NL) | 2017-11-01 | — | — | EP | disclosed |
| EP-3233974-A1 | A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AS WELL AS THE PRODUCTS OBTAINED THEREFROM | SABIC Global Technologies B.V. (NL) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016102694-A1 | PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-06-30 | — | — | WO | disclosed |
| WO-2016097203-A1 | A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AS WELL AS THE PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-06-23 | — | — | WO | disclosed |