Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422531 | 1.00 | AKT1 (0.56) | AKT1TSHRALDH1A1CES1CES2 | |
| SCHEMBL2185852 | 0.79 | AKT1 (0.59) | AKT1TSHRALDH1A1CES1CES2 | |
| SCHEMBL630088 | 0.77 | AKT1 (0.56) | AKT1TSHRALDH1A1CES1CES2 | |
| SCHEMBL23328518 | 0.77 | AKT1 (0.56) | AKT1TSHRALDH1A1CES1CES2 | |
| SCHEMBL313871 | 0.77 | AKT1 (0.56) | AKT1TSHRALDH1A1CES1CES2 | |
| SCHEMBL5520722 | 0.75 | NR4A1 (0.50) | AKT1ALDH1A1TGM2CYP3A4CYP2C19 | |
| SCHEMBL108144 | 0.74 | AKT1 (0.54) | AKT1TSHRALDH1A1CES1CES2 | |
| SCHEMBL7190703 | 0.74 | ALDH5A1 (0.58) | TSHRALDH1A1MAPK1CYP3A4MAPT | |
| SCHEMBL17845920 | 0.72 | AKT1 (0.41) | AKT1TSHRALDH1A1CES1CES2 | |
| SCHEMBL20995401 | 0.72 | AKT1 (0.52) | AKT1TSHRALDH1A1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1073 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229483-A | Amide potassium complex for catalyzing lactide ring-opening polymerization and preparation method thereof | 北京服装学院 | 2023-12-15 | — | — | CN | claimed |
| CN-116120302-A | 2, 3-disubstituted oxazolidine 4-ketone compound and preparation and application thereof | 上海鸿恒生物医药科技有限公司 | 2023-05-16 | — | — | CN | claimed |
| US-20220380608-A1 | Flame Retardant Mechanical Foam | STAHL INTERNATIONAL B.V. (NL) | 2022-12-01 | — | — | US | claimed |
| CN-114846090-A | Flame-retardant mechanical foam | 斯塔尔国际有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114262307-A | 3- (3-cyclopropane substituted phenyl-4-thiazolinone) -N-aryl benzamide compound and application thereof | 上海鸿恒生物医药科技有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-114262325-A | 3- (3- (heteroaryl) -4-thiazolinone) -N-aryl benzamide compound and synthesis and application thereof | 上海鸿恒生物医药科技有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-114262305-A | Alkynyl-substituted thiazolinone-based-N-aryl benzamide compound and preparation method and application thereof | 上海鸿恒生物医药科技有限公司 | 2022-04-01 | — | — | CN | claimed |
| WO-2021133169-A1 | FLAME RETARDANT MECHANICAL FOAM | STAHL INTERNATIONAL B.V. (NL) | 2021-07-01 | — | — | WO | claimed |
| CN-107207421-B | Novel trifluoromethylpropionamide derivatives | 豪夫迈·罗氏有限公司 | 2021-04-20 | — | — | CN | claimed |
| US-20200306253-A1 | Therapeutic Modulators of the Reverse Mode of ATP Synthase | FORREST MICHAEL DAVID (GB) | 2020-10-01 | — | — | US | claimed |
| EP-0003081-A2 | Thiazolidinecarbothioamides, their preparation, compositions and use as insecticides | ELI LILLY AND COMPANY (US) | 1979-07-25 | — | — | EP | claimed |
| EP-0002938-A2 | Novel heterocyclic carbothioamides, compositions containing them, their preparation and use | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | claimed |
| EP-0002939-A2 | Novel carbothioamides, compositions containing them and their preparation | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | claimed |
| EP-0001149-A1 | Process for the preparation of 3-bromomethyl-3-cephem-sulphoxide derivatives | GIST-BROCADES N.V. (NL) | 1979-03-21 | — | — | EP | claimed |
| US-4107138-A | Phosphonous and thiophosphonous acid ethers as stabilizers for organic materials | SANDOZ LTD. (CH) | 1978-08-15 | — | — | US | claimed |
| US-4087408-A | Bromine and phosphorus containing polyester | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | claimed |
| US-3997534-A | PARASITICIDES, NEMATOCIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-14 | — | — | US | claimed |
| US-3966932-A | PLANTSORGANISMS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |
| US-3962259-A | TRANQUILIZERS, ANALGETIC AGENTS | AMERICAN HOECHST CORPORATION (US) | 1976-06-08 | — | — | US | claimed |
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200306253-A1 | Therapeutic Modulators of the Reverse Mode of ATP Synthase | ATP5ME, ATP5F1A, ATP5MG | AKT1 2402/4885TSHR 4201/4885ALDH1A1 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.