Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975368 | 1.00 | F9 (0.48) | F9PLAUKMT2AALDH1A1GAA | |
| SCHEMBL17846921 | 0.84 | KMT2A (0.56) | KMT2AALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL27296339 | 0.83 | F9 (0.46) | F9PLAUKMT2AALDH1A1GAA | |
| SCHEMBL10974859 | 0.79 | F9 (0.43) | F9PLAUKMT2AALDH1A1GAA | |
| SCHEMBL21415510 | 0.77 | HPGD (0.56) | F9PLAUKMT2AALDH1A1GAA | |
| SCHEMBL20097882 | 0.77 | HPGD (0.56) | F9PLAUKMT2AALDH1A1GAA | |
| SCHEMBL10976293 | 0.77 | GLA (0.51) | KMT2AALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL17846934 | 0.77 | GLA (0.51) | KMT2AALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL10728543 | 0.76 | CYP3A4 (0.52) | KMT2AALDH1A1GAATSHRCYP3A4 | |
| SCHEMBL14122546 | 0.75 | F9 (0.45) | F9PLAUKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10172814-B2 | Substituted pyridyl-cycloalkyl-carboxylic acids, compositions containing them and medical uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-01-08 | — | — | US | disclosed |
| US-20170354620-A1 | SUBSTITUTED PYRIDYL-CYCLOALKYL-CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING THEM AND MEDICAL USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-12-14 | — | — | US | disclosed |
| EP-3233802-A1 | SUBSTITUTED PYRIDYL-CYCLOALKYL-CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING THEM AND MEDICAL USES THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097013-A1 | SUBSTITUTED PYRIDYL-CYCLOALKYL-CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING THEM AND MEDICAL USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10172814-B2 | Substituted pyridyl-cycloalkyl-carboxylic acids, compositions containing them and medical uses thereof | PTGER1, PTGES, PTGES3 | F9 2818/4885PLAU 2585/4885KMT2A 3177/4885 |
| US-20170354620-A1 | SUBSTITUTED PYRIDYL-CYCLOALKYL-CARBOXYLIC ACIDS, COMPOSITIONS CONTAINING THEM AND MEDICAL USES THEREOF | PTGER1, PTGES, PTGES3 | F9 2818/4885PLAU 2585/4885KMT2A 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.