Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5688132 | 0.85 | KMT2A (0.56) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL12443610 | 0.84 | SMN1; SMN2 (0.62) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL19112997 | 0.84 | KMT2A (0.55) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL184399 | 0.83 | HSD17B10 (0.66) | KMT2AGAAHSD17B10HPGDGPR139 | |
| SCHEMBL161881 | 0.82 | KMT2A (0.81) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL1753831 | 0.82 | KMT2A (0.81) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL161880 | 0.82 | GAA (0.81) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL6889431 | 0.82 | GAA (0.87) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL27727377 | 0.82 | GAA (0.87) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL19112848 | 0.82 | KMT2A (0.53) | KMT2AGAAHSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097394-A1 | BICYCLIC SULFONAMIDE DERIVATIVES AS INVERSE AGONISTS OF RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR GAMMA (T)) | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-23 | — | — | WO | claimed |