Somatostatin Receptor Ligand

Somatostatin Receptor Ligand

SCHEMBL1784775

CC(=O)O.CC(O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C(C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](C)N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC1=O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SSTR1SSTR2SSTR3SSTR4SSTR5

The experimentally established mechanism targets of Somatostatin Receptor Ligand. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SSTR4 known ✓ P31391 13/20 0.81
SSTR5 known ✓ P35346 11/20 0.81
SSTR2 known ✓ P30874 10/20 0.81
SSTR1 known ✓ P30872 10/20 0.81
SSTR3 known ✓ P32745 10/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Somatostatin Receptor Ligand SCHEMBL5698935 0.99 SSTR4 (0.80) SSTR4SSTR5SSTR2SSTR1SSTR3
Somatostatin SCHEMBL29350200 0.99 SSTR4 (0.83) SSTR4SSTR5SSTR2SSTR1SSTR3
Somatostatin Receptor Ligand SCHEMBL8482 0.99 SSTR4 (0.83) SSTR4SSTR5SSTR2SSTR1SSTR3
Somatostatin Receptor Ligand SCHEMBL29386529 0.99 SSTR4 (0.83) SSTR4SSTR5SSTR2SSTR1SSTR3
Somatostatin Receptor Ligand SCHEMBL3046327 0.99 SSTR4 (0.83) SSTR4SSTR5SSTR2SSTR1SSTR3
Somatostatin Receptor Ligand SCHEMBL31432768 0.99 SSTR4 (0.83) SSTR4SSTR5SSTR2SSTR1SSTR3
Somatostatin Receptor Ligand SCHEMBL16062971 0.99 SSTR4 (0.83) SSTR4SSTR5SSTR2SSTR1SSTR3
Somatostatin Receptor Ligand SCHEMBL12548326 0.99 SSTR4 (0.83) SSTR4SSTR5SSTR2SSTR1SSTR3
Somatostatin SCHEMBL21361053 0.99 SSTR4 (0.83) SSTR4SSTR5SSTR2SSTR1SSTR3
SCHEMBL29368491 0.99 SSTR4 (0.83) SSTR4SSTR5SSTR2SSTR1SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115192542-B Oral nanometer drug delivery system mediated by small molecule nutrient substances 四川大学 2023-09-08 CN claimed
CN-115192542-A Oral nano drug delivery system mediated by small molecular nutrient substances 四川大学 2022-10-18 CN claimed
CN-115040495-A Oral nano drug delivery system mediated by small molecular nutrient substances 四川大学 2022-09-13 CN claimed
CN-112755005-B Oral nano drug delivery system mediated by small molecular nutrient substances 四川大学 2022-05-13 CN claimed
CN-111303473-B Preparation method of powder injection rubber plug 北京市新里程医药科技有限公司 2022-03-18 CN claimed
CN-112755005-A Oral nano drug delivery system mediated by small molecular nutrient substances 四川大学 2021-05-07 CN claimed
US-20210106538-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF BIOMACROMOLECULE AGENTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2021-04-15 US claimed
CN-112641757-A Carrier for transmembrane delivery of molecules and preparation method thereof 中国药科大学 2021-04-13 CN claimed
CN-111471206-A Preparation method of rubber plug for powder injection of somatostatin and derivatives thereof 北京市新里程医药科技有限公司 2020-07-31 CN claimed
CN-111303473-A Preparation method of powder injection rubber plug 北京市新里程医药科技有限公司 2020-06-19 CN claimed
EP-3471778-A2 COMPOSITIONS AND METHODS FOR DELIVERY OF BIOMACROMOLECULE AGENTS The Regents of The University of Michigan (US) 2019-04-24 EP claimed
CN-105412935-B One kind being based on the nanoparticle and preparation method thereof of N- (2- hydroxypropyl) methacrylamide polymer 四川大学 2019-02-19 CN claimed
WO-2018156617-A2 COMPOSITIONS AND METHODS FOR DELIVERY OF POLYMER / BIOMACROMOLECULE CONJUGATES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2018-08-30 WO claimed
WO-2017223085-A2 COMPOSITIONS AND METHODS FOR DELIVERY OF BIOMACROMOLECULE AGENTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2017-12-28 WO claimed
US-20110124563-A1 PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE OF SOMATOSTATIN OR AN ANALOGUE THEREOF GP PHARM S.A. 2011-05-26 US claimed
EP-2223684-A2 PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE OF SOMATOSTATIN OR AN ANALOGUE THEREOF GP Pharm S.A. (ES) 2010-09-01 EP claimed
CN-1508152-A Somatostatin full-synthesis method 常州市第四制药厂有限公司 2004-06-30 CN claimed
US-4835138-A Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities MERCK & CO., INC. (US) 1989-05-30 US claimed
US-12622922-B2 Compositions and methods for metal containing formulations capable of modulating immune response THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-05-12 US disclosed
CN-1508152-A Somatostatin full-synthesis method 常州市第四制药厂有限公司 2004-06-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622922-B2 Compositions and methods for metal containing formulations capable of modulating immune response STING1, CGAS, TLR3 SSTR4 3263/4885SSTR5 3634/4885SSTR2 2182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.