Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.40 |
| ▸ | MAOA | P21397 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3643405 | 0.79 | MAOB (0.54) | MAOBMAOAHDAC6 | |
| SCHEMBL17848261 | 0.76 | MAOB (0.64) | MAOBMAOAMAPT | |
| SCHEMBL3218774 | 0.76 | MAOB (0.58) | MAOBMAOA | |
| SCHEMBL114699 | 0.72 | CYP11B1 (0.43) | HDAC1 | |
| SCHEMBL3641442 | 0.72 | MAOB (0.59) | MAOBMAOAHDAC6 | |
| SCHEMBL17848427 | 0.71 | MAOB (0.44) | MAOBMAOAMAPT | |
| SCHEMBL17848424 | 0.71 | MAOB (0.44) | MAOBMAOAMAPT | |
| SCHEMBL5748867 | 0.70 | LTA4H (0.44) | MAPT | |
| SCHEMBL874158 | 0.69 | ERN1 (0.56) | POLBMAPT | |
| SCHEMBL4420136 | 0.69 | APP (0.53) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097345-A1 | LABELLED CHROMONE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |