SCHEMBL17849185

CO[C@@H]1C(CO)O[C@H](O[C@@H]2C(OC=O)O[C@@H](O[C@@H]3C(CO)O[C@H](O[C@@H]4C(OC=O)O[C@@H](OCCN)[C@@H](O)C4O)[C@@H](NC(C)=O)C3O)[C@@H](O)C2O)[C@@H](NC(C)=O)C1O

nearest known ligand 0.54

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	LGALS3	P17931	8/20	0.54

▸	LGALS8	O00214	2/20	0.54

▸	LGALS4	P56470	2/20	0.54

▸	IGF2R	P11717	2/20	0.47

▸	CHIA	Q9BZP6	1/20	0.43

▸	MAPK1	P28482	1/20	0.43

▸	LGALS7; LGALS7B	P47929	2/20	0.42

▸	LGALS1	P09382	1/20	0.42

▸	LGALS9	O00182	2/20	0.41

▸	CD69	Q07108	1/20	0.41

▸	HPSE	Q9Y251	2/20	0.39

▸	AMY2A	P04746	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16641974	1.00	LGALS3 (0.54)	LGALS3LGALS8LGALS4IGF2RCHIA
SCHEMBL16641977	0.95	LGALS3 (0.58)	LGALS3LGALS8LGALS4IGF2RCHIA
SCHEMBL16996680	0.95	LGALS3 (0.58)	LGALS3LGALS8LGALS4IGF2RCHIA
SCHEMBL16996679	0.95	LGALS3 (0.58)	LGALS3LGALS8LGALS4IGF2RCHIA
SCHEMBL16999977	0.95	LGALS3 (0.58)	LGALS3LGALS8LGALS4IGF2RCHIA
SCHEMBL17849186	0.90	LGALS3 (0.54)	LGALS3LGALS8LGALS4CHIAMAPK1
SCHEMBL20175842	0.90	LGALS3 (0.52)	LGALS3LGALS8LGALS4CHIAMAPK1
SCHEMBL18494820	0.88	LGALS3 (0.53)	LGALS3LGALS8LGALS4IGF2RCHIA
SCHEMBL18494405	0.88	LGALS3 (0.53)	LGALS3LGALS8LGALS4IGF2RCHIA
SCHEMBL16063647	0.88	LGALS3 (0.53)	LGALS3LGALS8LGALS4IGF2RCHIA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9370583-B2	Coagulation factor VII polypeptides	NOVO NORDISK HEALTHCARE AG (CH)	2016-06-21	—	—	US	disclosed