Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | GLI1 | P08151 | 1/20 | 0.34 |
| ▸ | GLI2 | P10070 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16572623 | 1.00 | ALDH1A1 (0.51) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL16572620 | 0.91 | ALDH1A1 (0.56) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL16283146 | 0.87 | ALDH1A1 (0.49) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL11308182 | 0.82 | TDP1 (0.55) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL11305011 | 0.82 | TDP1 (0.55) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL11124516 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL11306516 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL11306958 | 0.78 | TDP1 (0.53) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL11428553 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TDP1PTGS1MEN1CYP2D6 | |
| SCHEMBL11145080 | 0.77 | TDP1 (0.59) | ALDH1A1TDP1PTGS1MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371273-B2 | Ether-amide compounds and preparation and uses thereof | RHODIA OPERATIONS (FR) | 2016-06-21 | — | — | US | disclosed |