Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852823 | 0.78 | CA12 (0.47) | CA12CA1CA2CA9 | |
| SCHEMBL17849602 | 0.72 | CA12 (0.34) | CA12CA1CA2CA9 | |
| SCHEMBL30912244 | 0.70 | MEN1 (0.48) | — | |
| SCHEMBL8105009 | 0.68 | CA12 (0.42) | CA12CA1CA2CA9 | |
| SCHEMBL17849590 | 0.67 | TRPA1 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL20243935 | 0.66 | — | — | |
| SCHEMBL16020287 | 0.66 | — | — | |
| SCHEMBL19810744 | 0.66 | CA12 (0.37) | CA12CA1CA2CA9 | |
| SCHEMBL5033603 | 0.66 | — | — | |
| SCHEMBL9099675 | 0.64 | TRPA1 (0.61) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371336-B2 | Compounds for treating spinal muscular atrophy | PTC THERAPEUTICS, INC. (US) | 2016-06-21 | — | — | US | disclosed |