SCHEMBL17849633

SCHEMBL17849633

CC1(C)c2cccc3ccc4cc(-c5ccc6cc(N(c7ccccc7)c7ccccc7)ccc6c5)cc1c4c23

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
ACMSD Q8TDX5 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CHRND Q07001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849640 0.98 LPL (0.36) LPLLIPGHSD17B1HSD17B2CHRNA1
SCHEMBL17849636 0.96 LPL (0.36) LPLLIPGHSD17B1HSD17B2ACMSD
SCHEMBL13888831 0.94 LPL (0.36) LPLLIPGHSD17B1HSD17B2ACMSD
SCHEMBL13888800 0.94 LPL (0.34) LPLLIPGHSD17B1HSD17B2
SCHEMBL13888803 0.94 LPL (0.34) LPLLIPG
SCHEMBL17849608 0.94 LPL (0.34) LPLLIPG
SCHEMBL13888806 0.94 LPL (0.34) LPLLIPG
SCHEMBL13888804 0.94 LPL (0.34) LPLLIPG
SCHEMBL17849616 0.92 LPL (0.33) LPLLIPG
SCHEMBL17849627 0.92 PDK2 (0.32) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed