SCHEMBL17849684

SCHEMBL17849684

CC1(C)c2cccc3ccc4cc(-c5ccc(N(c6ccc(C#N)cc6)c6ccc(-c7cccnc7)cc6)nc5)cc1c4c23

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 8/20 0.43
CYP11B1 P15538 7/20 0.43
CYP17A1 P05093 3/20 0.43
NPY5R Q15761 1/20 0.35
ABL1 P00519 1/20 0.35
PDGFRB P09619 1/20 0.35
BCR P11274 1/20 0.35
PDGFRA P16234 1/20 0.35
PRKCA P17252 1/20 0.35
CYP2A6 P11509 1/20 0.34
CYP19A1 P11511 5/20 0.34
PARP1 P09874 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA5 P30532 1/20 0.32
CHRNA4 P43681 1/20 0.32
GAK O14976 1/20 0.32
STK16 O75716 1/20 0.32
PIM1 P11309 1/20 0.32
AXL P30530 1/20 0.32
NEK2 P51955 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909666 0.93 CYP11B2 (0.48) CYP11B2CYP11B1CYP17A1NPY5RABL1
SCHEMBL15909645 0.87 CYP11B2 (0.45) CYP11B2CYP11B1CYP17A1NPY5RABL1
SCHEMBL17849666 0.86 CYP11B2 (0.51) CYP11B2CYP11B1CYP17A1NPY5RCYP19A1
SCHEMBL15909621 0.86 PARP1 (0.32) PARP1
SCHEMBL15909664 0.85 CYP11B2 (0.50) CYP11B2CYP11B1CYP17A1NPY5RCYP19A1
SCHEMBL17849677 0.84 PARP1 (0.32) PARP1
SCHEMBL17849680 0.84 GRM2 (0.32)
SCHEMBL15909662 0.84 CYP11B2 (0.43) CYP11B2CYP11B1CYP17A1NPY5RABL1
SCHEMBL15909623 0.82 CYP11B2 (0.44) CYP11B2CYP11B1CYP17A1CYP2A6CYP19A1
SCHEMBL17849647 0.82 MYC (0.37) PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed