Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 4/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15855471 | 0.87 | MAPT (0.50) | MAPTALOX15KDM4EHPGDCYP1A2 | |
| SCHEMBL17849732 | 0.80 | MAPK14 (0.34) | ALOX15HPGDCYP3A4HSD17B10CDC25B | |
| SCHEMBL17740701 | 0.80 | ALDH1A1 (0.45) | MAPTALOX15KDM4EHPGDCYP3A4 | |
| SCHEMBL783331 | 0.79 | MAPT (0.57) | MAPTALOX15KDM4EHPGDALDH1A1 | |
| SCHEMBL17849728 | 0.78 | MAPT (0.49) | MAPTALOX15KDM4EHPGDCYP1A2 | |
| SCHEMBL12333415 | 0.78 | MAPT (0.55) | MAPTALOX15KDM4EHPGDCYP1A2 | |
| SCHEMBL15855467 | 0.78 | HPGD (0.36) | ALOX15HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20204499 | 0.77 | ALDH1A1 (0.39) | MAPTALOX15KDM4EHPGDCYP3A4 | |
| SCHEMBL2787546 | 0.77 | MAPT (0.56) | MAPTALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL22433826 | 0.74 | MAPT (0.56) | MAPTALOX15KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9728728-B2 | Compound and organic light-emitting device using same | LG CHEM, LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-9373793-B2 | Compound and organic light-emitting device using same | LG CHEM, LTD. (KR) | 2016-06-21 | — | — | US | disclosed |