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SCHEMBL17849807

SCHEMBL17849807

CNCC(=O)N[C@@H](CSC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CS)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.44
▸ NPY5R Q15761 8/20 0.44
▸ NPY1R P25929 8/20 0.44
▸ NPY2R P49146 5/20 0.41
▸ GRPR P30550 1/20 0.37
▸ NPBWR1 P48145 1/20 0.36
▸ IL23R Q5VWK5 1/20 0.35
▸ OPRL1 P41146 2/20 0.35
▸ TLR2 O60603 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17349862 0.94 NPY4R (0.44) NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL17849801 0.93 NPY4R (0.44) NPY4RNPY5RNPY1RNPY2RIL23R
SCHEMBL18264800 0.93 NPY4R (0.45) NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL18264759 0.91 NPY4R (0.45) NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL18264745 0.91 NPY4R (0.45) NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL18264766 0.91 NPY4R (0.42) NPY4RNPY5RNPY1RNPY2RNPBWR1
SCHEMBL18264771 0.91 NPY4R (0.42) NPY4RNPY5RNPY1RNPY2RNPBWR1
SCHEMBL18264812 0.87 NPY4R (0.46) NPY4RNPY5RNPY1RNPY2R
SCHEMBL20724927 0.86 NPY4R (0.46) NPY4RNPY5RNPY1RNPY2RIL23R
SCHEMBL18264830 0.84 TLR2 (0.42) NPY4RNPY5RNPY1RNPY2RGRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10570178-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2020-02-25 — — US disclosed
US-9504763-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2016-11-29 — — US disclosed
US-9371367-B1 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2016-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570178-B2 Selective delivery molecules and methods of use SLC7A1, SLC47A1, SLC47A2 NPY4R 1455/4885NPY5R 2621/4885NPY1R 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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