SCHEMBL18264759

CSC[C@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)NC(CS)C(N)=O

nearest known ligand 0.45

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	15/20	0.45

▸	NPY5R	Q15761	9/20	0.45

▸	NPY1R	P25929	9/20	0.45

▸	NPY2R	P49146	6/20	0.42

▸	GRPR	P30550	1/20	0.37

▸	NPBWR1	P48145	1/20	0.37

▸	OPRL1	P41146	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18264745	1.00	NPY4R (0.45)	NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL18264830	0.93	TLR2 (0.42)	NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL17349862	0.92	NPY4R (0.44)	NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL17849807	0.91	NPY4R (0.44)	NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL17849801	0.91	NPY4R (0.44)	NPY4RNPY5RNPY1RNPY2ROPRL1
SCHEMBL18264800	0.91	NPY4R (0.45)	NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL18264852	0.89	NPY4R (0.43)	NPY4RNPY5RNPY1RNPY2RNPBWR1
SCHEMBL17849852	0.88	NPY4R (0.52)	NPY4RNPY5RNPY1RNPY2RNPBWR1
SCHEMBL17562161	0.88	NPY5R (0.38)	NPY4RNPY5RNPY1RNPY2RGRPR
SCHEMBL21753988	0.88	NPY4R (0.42)	NPY4RNPY5RNPY1RNPY2RNPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9504763-B2	Selective delivery molecules and methods of use	AVELAS BIOSCIENCES, INC. (US)	2016-11-29	—	—	US	disclosed