Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 8/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18372961 | 0.92 | FAAH (0.39) | LMNAALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL12111239 | 0.90 | FAAH (0.37) | LMNAALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL16299335 | 0.83 | FAAH (0.36) | LMNAMAPTL3MBTL1FAAHTSHR | |
| SCHEMBL17849906 | 0.82 | FAAH (0.33) | LMNAFAAHTSHRMEN1KMT2A | |
| SCHEMBL18766737 | 0.82 | HPGD (0.37) | LMNAALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL16299401 | 0.80 | FAAH (0.36) | LMNAMAPTFAAHTSHRMEN1 | |
| SCHEMBL16299327 | 0.77 | FAAH (0.37) | LMNAMAPTL3MBTL1FAAHTSHR | |
| SCHEMBL18602758 | 0.77 | FAAH (0.39) | LMNAL3MBTL1FAAHTSHRKMT2A | |
| SCHEMBL17849881 | 0.76 | FAAH (0.34) | LMNAFAAHTSHRMEN1POLB | |
| SCHEMBL13082978 | 0.76 | FAAH (0.38) | LMNAMAPTFAAHTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371283-B2 | Polycyclic tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2016-06-21 | — | — | US | disclosed |