SCHEMBL17849920

SCHEMBL17849920

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nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 19/20 1.00
▸ RIMKLA Q8IXN7 1/20 0.64
▸ NAALAD2 Q9Y3Q0 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15278119 1.00 FOLH1 (1.00) FOLH1RIMKLANAALAD2
SCHEMBL17849539 0.96 FOLH1 (0.92) FOLH1RIMKLANAALAD2
SCHEMBL18412142 0.92 FOLH1 (0.85) FOLH1RIMKLANAALAD2
SCHEMBL19360024 0.91 FOLH1 (0.83) FOLH1RIMKLANAALAD2
SCHEMBL20018424 0.91 FOLH1 (0.83) FOLH1RIMKLANAALAD2
SCHEMBL29597774 0.90 FOLH1 (0.82) FOLH1RIMKLANAALAD2
SCHEMBL10060822 0.90 FOLH1 (0.81) FOLH1RIMKLANAALAD2
SCHEMBL13177561 0.90 FOLH1 (0.81) FOLH1RIMKLANAALAD2
SCHEMBL30967340 0.89 FOLH1 (0.80) FOLH1RIMKLANAALAD2
SCHEMBL29598755 0.89 FOLH1 (0.80) FOLH1RIMKLANAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023230729-A1 SYNTHETIC ANTIGEN RECEPTORS FOR COVALENT IMMUNE RECRUITERS AND METHODS AND USES THEREOF MCMASTER UNIVERSITY (CA) 2023-12-07 — — WO disclosed
US-20230302164-A1 PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-09-28 — — US disclosed
US-20230173112-A1 PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-06-08 — — US disclosed
US-9371360-B2 Homomultivalent and heteromultivalent inhibitors of prostate specific membrane antigen (PSMA) and uses thereof THE JOHNS HOPKINS UNIVERSITY (US) 2016-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230173112-A1 PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy PSMA1, PSMA2, FOLH1 FOLH1 3/4885RIMKLA 1299/4885NAALAD2 198/4885
US-20230302164-A1 PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy PSMA1, PSMA2, FOLH1 FOLH1 3/4885RIMKLA 1290/4885NAALAD2 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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