Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.81 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.53 |
| ▸ | GLP1R | P43220 | 3/20 | 0.53 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13177561 | 1.00 | FOLH1 (0.81) | FOLH1NOD1GLP1RRIMKLANAALAD2 | |
| SCHEMBL18412142 | 0.97 | FOLH1 (0.85) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL24590790 | 0.93 | FOLH1 (0.70) | FOLH1NOD1GLP1R | |
| SCHEMBL15003786 | 0.90 | NOD1 (0.65) | FOLH1NOD1GLP1R | |
| SCHEMBL19433447 | 0.90 | FOLH1 (0.64) | FOLH1NOD1GLP1RRIMKLANAALAD2 | |
| SCHEMBL10060824 | 0.90 | FOLH1 (0.64) | FOLH1NOD1GLP1R | |
| SCHEMBL16645331 | 0.90 | NOD1 (0.65) | FOLH1NOD1GLP1R | |
| SCHEMBL23252356 | 0.90 | FOLH1 (0.67) | FOLH1NOD1GLP1RRIMKLANAALAD2 | |
| SCHEMBL20341086 | 0.90 | FOLH1 (0.70) | FOLH1NOD1GLP1R | |
| SCHEMBL17849920 | 0.90 | FOLH1 (1.00) | FOLH1RIMKLANAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348405-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSTY | 2023-11-02 | — | — | US | disclosed |
| US-11661402-B2 | PSMA-targeting compounds and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-05-30 | — | — | US | disclosed |
| US-9776977-B2 | PSMA-targeting compounds and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-10-03 | — | — | US | disclosed |
| EP-3222617-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | The Johns Hopkins University (US) | 2017-09-27 | — | — | EP | disclosed |
| EP-2408755-B1 | Urea-based peptide compounds useful for detecting inter alia prostate cancer | UNIV JOHNS HOPKINS (US) | 2017-05-03 | — | — | EP | disclosed |
| US-9056841-B2 | PSMA-targeting compounds and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-06-16 | — | — | US | disclosed |
| US-20150104387-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-04-16 | — | — | US | disclosed |
| US-20120009121-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009121-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | FOLH1, KLK3, PSMA2 | FOLH1 1/4885NOD1 4800/4885GLP1R 1594/4885 |
| US-20230348405-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | KLK3, FOLH1, SPR | FOLH1 2/4885NOD1 4337/4885GLP1R 1561/4885 |
| US-20150104387-A1 | PSMA-TARGETING COMPOUNDS AND USES THEREOF | FOLH1, KLK3, PSMA2 | FOLH1 1/4885NOD1 4800/4885GLP1R 1594/4885 |
| US-11661402-B2 | PSMA-targeting compounds and uses thereof | KLK3, FOLH1, SPR | FOLH1 2/4885NOD1 4337/4885GLP1R 1561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.